scEve

Modality imputation using downloaded or custom scEve model.

Download model

Download pretrained model from scParadise repository.

sceve.available_models	Download dataframe with available trained scEve models.
sceve.download_model	Download pretrained tuned model for highly accurate cell surface protein abundance imputation.

Model training and tuning

Train custom scEve model using your own multimodal dataset. Hyperparameter tuning is also available to achieve better model performance.

sceve.train	Train custom scEve model using MuData object with different modalities.
sceve.hyperparameter_tuning	Hyperparameter tuning using the automatic model optimization framework Optuna.
sceve.train_tuned	Train the scEve model using parameters tuned by the 'scparadise.sceve.hyperparameter_tuning' function.

Imputation

Modality imputation using downloaded or custom scEve model.

sceve.predict

Predict (impute) the second modality in cells using the pretrained scEve model.